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目的评价二巯丁二酸胶囊(DMSA)与依地酸钙钠注射液(CaNa2-EDTA)治疗慢性铅中毒的成本和效果。方法采用药物学经济学的成本-效果分析法对两组治疗方案进行回顾性分析评价。结果 DMSA组与CaNa2-EDTA组有效率分别为96.8%与96.9%,成本分别为422.36元与463.40元,成本-效果比分别为4.365与4.783,增长的成本-效果比分别为0与373.09。结论 DMSA胶囊相对于CaNa2-EDTA注射液治疗慢性铅中毒具有明显药物经济学优势。
Objective To evaluate the cost and effectiveness of DMSA and CaNa2-EDTA in the treatment of chronic lead poisoning. Methods The cost-effectiveness analysis method of pharmacoeconomics was used to retrospectively evaluate the two treatment regimens. Results The effective rates of DMSA group and CaNa2-EDTA group were 96.8% and 96.9% respectively, the costs were 422.36 yuan and 463.40 yuan respectively, and the cost-effectiveness ratios were 4.365 and 4.783 respectively. The cost-effectiveness ratios were 0 and 373.09 respectively. Conclusion DMSA capsule has obvious pharmacological and economic advantages compared with CaNa2-EDTA injection in the treatment of chronic lead poisoning.