用光镜和电镜对自然吸入茶尘的大鼠肺进行观察。可见茶尘在肺内沉着,形成气道炎、肺泡炎、间质肉芽肿、轻度纤维增生和较重的肺气肿。网状纤维增生发生于染尘后第6个月,胶原纤维增生发生于第9个月。Ⅰ型肺泡上皮细胞变性、坏死、数量减少。Ⅱ型细胞增多。肺泡隔增厚、毛细血管周围纤维母细胞和胶原纤维均有增生,提示茶尘可引起肺组织改变和损害。 The lungs of rats exposed to tea dust were observed by light and electron microscopy. Tea dust can be seen in the lungs calm, the formation of airways inflammation, alveolitis, interstitial granuloma, mild fibrosis and severe emphysema. Reticular fibrosis occurred in the first 6 months after dying, collagen fibrosis occurred in the 9th month. Type I alveolar epithelial cells degeneration, necrosis, the number decreased. Type II cells increased. Alveolar septum thickening, fibroblasts around the capillaries and collagen fibers are hyperplasia, suggesting that tea dust can cause lung tissue changes and damage.