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氯苯甲噻二嗪快速静脉注射可因血压在2～3分钟内快速下降从而导致心脑缺血症状及持久性损害.早先认为氯苯甲噻二嗪因有高度的蛋白结合作用,应予快速推注,缓慢注射则无效.以后的报道则显示,缓慢滴注20～30分钟可产生平稳的降压作用,而无组织缺血现象.本文显示,在治疗严重高血压时,静脉缓慢滴注氯苯甲噻二嗪可在短时间内有效地降低血压,缓解高血压危象,而无血压快速下降的危险.
Chlorpheniramine rapid intravenous injection can be due to rapid decline in blood pressure within 2 to 3 minutes, resulting in symptoms of cerebral ischemia and persistent damage .Chemchomethazine was previously thought to have a high degree of protein binding, should be Rapid bolus injection, slow injection is invalid.After the report shows that slow drip 20 to 30 minutes can produce a smooth antihypertensive effect, but no tissue ischemia.This article shows that in the treatment of severe hypertension, the slow intravenous drip Chlorpheniramine can effectively reduce blood pressure in a short time, relieve the crisis of hypertension, without the risk of rapid decline in blood pressure.