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本文追溯了本溪市1986年～1994年出生的围产儿24744例,其中畸形331例,发生率13.88‰,用统一表格调查了围产儿父母在怀孕前后所接触的各种化学、物理及生物性环境因素,分析它们与出生缺陷的关系,并作了多因素调整的相对危险性分析,证明有统计学显著意义的危险因素24类.其中危险性很强的因素有遗传因素、孕期发热感冒、孕期不热感冒、父亲吸烟、孕期职业噪声、服中草药和大气污染.作者还分析了上述诸因素的综合人群归因危险度,大小依次为:父母接触化学毒物、父亲吸烟、孕期感冒、重污染区大气污染、职业噪声、父亲饮酒等,并据此提出了防治措施.
This article traced 24,744 perinatal births in Benxi City from 1986 to 1994, of which 331 cases were abnormal, with a prevalence of 13.88 ‰. The chemical, physical and biological environments in which perinatal parents contacted before and after pregnancy were investigated by a unified table Factors, analysis of their relationship with birth defects, and made a relative risk analysis of multi-factor adjustment, to prove statistically significant risk factors 24. Of which the risk factors are genetic factors, pregnancy flu, pregnancy Smoking, smoking during pregnancy, occupational noise during pregnancy, Chinese herbal medicine and air pollution.The author also analyzed the attribution risk of the general population of the above factors in order of parents’ exposure to chemical poisons, father’s smoking, pregnancy flu and heavy polluted area Air pollution, occupational noise, father’s drinking, etc., and put forward the prevention and control measures accordingly.