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为了观察脂肪乳剂对肿瘤病人围手术期细胞免疫功能的影响，将14名病理证实的进展期胃肠道癌症病人分为二组，TPN-力能组，力能提供30％非蛋白热卡，TPN-葡萄糖组，葡萄糖提供100％非蛋白热卡。能量给予105kj·kg-1·d-1，N0．12g·kg-1·d-1，营养液以“全合一”液匀速输入，分别于术前、营养前、营养后4天抽取外周血测定T细胞亚群、NK细胞及IL-2细胞。结果表明，T亚群中CD3，CD4，CD8，NK细胞及IL－2分泌细胞在手术后明显下降，经TPN营养支持4天后回升。研究结论：（1）手术创伤降低机体细胞免疫功能。（2）20％力能提供30％非蛋白热卡可使手术创伤应激期机体免疫功能恢复。使创伤后免疫障碍病人，在TPN后细胞免疫恢复至术前水平，可以说明在创伤应激期脂肪乳剂的适量应用是有益的，并不产生细胞免疫抑制。
In order to observe the effect of fat emulsion on perioperative cellular immune function in cancer patients, 14 pathologically confirmed patients with advanced gastrointestinal cancer were divided into two groups. The TPN-power group was able to provide 30% non-protein heat calorie, In the TPN-glucose group, glucose provided 100% non-protein calorie. The energy is given at 105kj·kg-1·d-1, and N0.12g·kg-1·d-1. The nutrient solution is input at a uniform rate of the “all-in-one” liquid, and the peripheral blood is extracted before surgery, before nutrition, and 4 days after nutrition. Blood was measured for T cell subsets, NK cells, and IL-2 cells. The results showed that CD3, CD4, CD8, NK cells and IL-2 secreting cells in T subgroup decreased significantly after surgery, and recovered after 4 days of TPN nutritional support. Research conclusions: (1) Surgical trauma reduces cellular immune function. (2) 20% of the power to provide 30% non-protein fever can restore the body’s immune function during traumatic stress. In patients with post-traumatic immune disorders, cellular immune recovery after TPN to preoperative levels may indicate that the appropriate application of fat emulsion during traumatic stress period is beneficial and does not produce cellular immunosuppression.