少数以往或现正患有Graves病(甲状腺机能亢进)的病人可发生双侧眶内炎症;偶尔也可见于无甲亢者。这可能是一种独立的原因不明的器官特异性自身免疫病。但自身抗原的性质不明,在病人血清中尚未查到眼眶抗体。众所周知眼部病变常伴发于甲亢,但二者可先后相差数年。少数病人之眼病变可单独发生。眼病变多不受甲亢治疗的影响。关于Graves眼病发病机理的早年研究,均集中于与甲亢的关系和长效甲状腺刺激因子的作 A small number of patients with past or present Graves disease (hyperthyroidism) can develop bilateral orbital inflammation; occasionally can also be found in those without hyperthyroidism. This may be an independent, unexplained, organ-specific autoimmune disease. However, the nature of its own antigen is unknown, orbital antibodies have not been found in the patient’s serum. It is well known that ocular lesions are often associated with hyperthyroidism, but the difference between the two can be several years. A small number of patients with eye lesions can occur alone. Eye disease more than hyperthyroidism treatment. Early studies on the pathogenesis of Graves ophthalmology have focused on the relationship with hyperthyroidism and the long-acting thyroid stimulating factor