降钙素基因相关肽（CGRP）作为一种潜在的血管扩张剂可以用来调整发生冷激反应的外周循环。已经证实，雷诺病患者指部皮肤的外周血管神经丛缺乏CGRP。作者通过静脉注射CGRP观察这种物质对雷诺现象的疗效。1对象和方法伴严重雷诺现象和外周血管功能不全的患者10例，其中女性6例 Calcitonin gene-related peptide (CGRP), as a potential vasodilator, can be used to regulate the peripheral circulation in which cold shock occurs. It has been demonstrated that peripheral vascular plexus of finger skin of patients with Raynaud’s disease lacks CGRP. The authors observed the effect of this substance on Raynaud’s phenomenon by intravenous injection of CGRP. 1 object and method with severe Renault phenomenon and peripheral vascular insufficiency in 10 patients, including 6 females