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为进一步研究核黄素的新功能,进行了核黄素阻抑动物致畸作用的实验。实验大鼠分为三组,分别给予50μg、250μg和1000μg的大剂量核黄素灌胃一周,妊娠后各组包括对照组一律按0.75mg/kg体重的致畸农药“敌枯双”每天灌胃染毒一次,并继续按上述方法给予核黄素,以观察“敌枯双”染毒后孕鼠的一般情况,体重增长及血红蛋白影响。动物处死
In order to further study the new function of riboflavin, experiments were conducted to evaluate the teratogenic effects of riboflavin. The experimental rats were divided into three groups and given high doses of riboflavin 50μg, 250μg and 1000μg gavage for one week. After pregnancy, each group including the control group all 0.75mg / kg body weight of teratogenic pesticides “dwarf double” daily irrigation Stomach poisoned once, and continue to give riboflavin according to the above method to observe the general situation, weight gain and hemoglobin of pregnant rats after “enemy dizzy double” exposure. Animals were sacrificed