1 病例介绍 患儿男,14岁,于人院前10小时因与母亲口角后自服下异烟肼1瓶(0.1g/片),共100片,服后不久,即出现呕吐,吐出胃内容物伴少许胆汁,但未见药片吐出,随后患儿出现抽搐,表现为四肢强直,双眼上翻,神志不清,持续2～3分钟后自行缓解,30分钟后,又类似发作1次,遂送往医院。当时由于病人隐瞒病史,病因不明,门诊予以安定止惊,补液抗炎处理,当晚患儿又类似抽搐2次,第2天检查脑电图示:轻度异常。即以抽搐原因待查,癫痫?收入住院。人院查体:T 37℃,P 92次/分,R 12次/分,Bp 16/9kPa,患儿呈嗜睡状态,呼之会应,对答尚清晰,随后又入睡,双侧瞳孔等大等圆,对光反射存在,颈软、心肺听诊无殊,腹软, 1 case description Children male, 14 years old, 10 hours before the hospital due to self-submission with his mother after oral administration of a bottle of isoniazid (0.1g / tablet), a total of 100 tablets, shortly after the service, vomiting, spit stomach Contents with a little bile, but no pills spit out, followed by convulsions in children, manifested as limb stiffness, eyes up, unconsciousness, sustained 2 to 3 minutes after the self-remission, 30 minutes later, and a similar attack 1, Then sent to the hospital. At that time, the patient concealed the medical history, the etiology was unknown, and the clinic was stable and stopped alarmed. The fluid replacement and anti-inflammatory treatment was similar to convulsions twice that night. On the second day, the EEG examination showed mild abnormality. That is to check the cause of convulsions, epilepsy? Income hospitalization. People’s hospital examination: T 37 ℃, P 92 beats / min, R 12 beats / min, Bp 16 / 9kPa, children were lethargy state, call the call should be, the answer is clear, then fall asleep, bilateral pupils and other large Waiting for the presence of light reflex, neck soft, cardiopulmonary auscultation without special, abdomen soft,