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目的 探索手机短信管理模式对提高肺结核患者治疗依从性与成功率的意义.方法 采用分层整群抽样法,抽取安徽省6个县(区),2014年12月1 日至2015年12月31日发现并登记的符合条件的肺结核患者350例纳入本研究.随机分为干预组(160例)与对照组(190例).干预组采用手机短信管理模式对患者进行管理,定期进行结核病相关核心知识宣教,对照组采用传统督导模式进行管理.结果 干预组接受医务人员访视频次(t=3.93,P=0.000);访视率(x2=7.55,P=0.006);接受宣传率(x2=22.60),P=0.000)高于对照组,差异均有统计学意义.干预组治疗完成率、继续服药率高于对照组,差异均有统计学意义(x2=9.52、13.86,P=0.002、0.000).治疗中断率、漏服药率低于对照组,差异均有统计学意义(x2=10.41、28.54,P=0.001、0.000).卡预组患者2月末查痰率、6月末查痰率及6月末X线检查率均高于对照组,差异有统计学意义(x2=9.52、17.61、10.65,P=0.002、0.000、0.001).结论 手机短信管理模式可有效提高患者治疗依从性、治疗完成率,值得推广应用.“,”Objective To explore the significance of mobile phone text messaging on the management of TB patients in improving the treatment compliance and success rate,and to provide scientific evidence for the promtion of the new model and formulation of related polices and measures.Methods A total of 350 patients were included in the study,they were from six counties (districts) selected by stratified cluster sampling metod and were randomly divided into control group (190) and intervention group (160).Patients in intervention group were managed using mobile phone text messages in which TB related core knowledge was delivered regularly,while patients in control group were managed via traditional way.Results In general,the visit rate (x2=7.55,P=0.006),frequency of visit (t=3.93,P 0.000) andservice receiving rate (x2=22.60,P=0.000) of patients in intervention group were significantly higher than that in control group.Meanwhile,the treatment completion rate (x2 =9.52,P=0.002) and rate of adherence to treatment (x2 =13.86,P=0.000) were significantly higher among patients in intervention group compared to those in control group,however,the discontinued treatment rate (x2=10.41,P=0.001) and missing dose rate (x2=28.54,P=0.000) were significantly lower.The sputum smear rates both at the end of 2 months (x2 =9.52,P=0.002) and 6 months (x2=17.61,P=0.000) and X-ray examination rate at the end of 6 months (x2=10.65,P=0.001) were all significantly higher among patients in intervention group compared to those in control group.Conclusions Mobile phone text messaging on the management of TB patients may effectively improve the adherence to anti tuberculosis treatment of patients with TB as well as the treatment completion rate.Therefore,this management model should be widely encouraged to use.