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对付癌症的最大难题之一是为什么患者的免疫系统几乎总是不能消除癌细胞。研究者猜想肿瘤细胞的幸存是靠它能逃避免疫监察或是能阻抑免疫反应。而本期Science报道说,至少有一种癌细胞具有比单是逃避免疫监察更为高明的策略:它们杀灭了攻击它们的免疫细胞。瑞士有一个研究组表
One of the biggest problems in dealing with cancer is why the patient’s immune system can almost always eliminate cancer cells. The researchers suspect that the survival of tumor cells depends on whether it can escape immune surveillance or suppress the immune response. In this issue of Science, at least one cancer cell has a more sophisticated strategy than evading immune surveillance: they kill the immune cells that attack them. Switzerland has a study group table