巨细胞胶质母细胞瘤(giant cell glioblastoma,GCG)是一种特殊的胶质母细胞瘤亚型,在神经胶质瘤的分类中,世界卫生组织(WHO)将其作为一个胶质母细胞瘤独特的变种。其发病率约占颅内肿瘤的1%,约占胶质母细胞瘤的5%[1-2]。GCG是一种罕见的具有肿瘤特征与丰富的嗜酸性胞浆奇异的多核巨细胞肿瘤,其神经胶质细胞起源已经电子显微镜和 Giant cell glioblastoma (giant cell glioblastoma, GCG) is a special glioblastoma subtype, in the classification of glioma, the World Health Organization (WHO) as a glioblastoma Unique variant of the tumor. The incidence of intracranial tumors accounts for about 1%, accounting for about 5% of glioblastoma [1-2]. GCG is a rare multinucleated giant cell tumor with tumorous features and abundant eosinophilic cytoplasm. Its origin of glial cells has been studied by electron microscopy and