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表皮生长因子受体(EGF-R)是原癌基因。c-erbB-1(也称HER-1)的表达产物,它与肿瘤形成的关系日渐受到人们的重视。本研究采用免疫组化方法检测正常宫颈粘膜。宫颈上皮异型增生及宫颈鳞癌组织中EGF-R的表达,探讨EGF-R与宫颈癌发生及生物学行为?
Epidermal growth factor receptor (EGF-R) is a protooncogene. The expression product of c-erbB-1 (also known as HER-1), its relationship with tumor formation has attracted more and more attention. In this study, immunohistochemistry was used to detect normal cervical mucosa. Cervical epithelial dysplasia and cervical squamous cell carcinoma EGF-R expression, to explore the EGF-R and cervical carcinogenesis and biological behavior?