地鼠肾组织培养狂犬病疫苗(简称组苗),在我国尚属一种新的生物制品,1980年正式使用,1981年取代羊脑狂犬病疫苗。经过几年应用,预防狂犬病收到一定效果,未出现羊脑苗所致的严重变态反应。但我省自1981年发生狂犬轻度咬伤注射组苗无效病例,随着组苗使用量增加,这类病例亦不断上升。因此,我们于1983～1988年对注射组苗仍发病者进行了调查。 调查对象和方法 本次调查采用回顾性流行病学个案调查方法,统 Rabbit kidney tissue culture rabies vaccine (referred to as group vaccine), in our country is still a new biological products, formally used in 1980, in 1981 to replace the sheep brain rabies vaccine. After several years of application, the prevention of rabies has received some results, did not appear severe headache caused by allergic rhinitis. However, our province since 1981 rabies mild bite injection group vaccine ineffective cases, with the use of group vaccine increased, such cases are also rising. Therefore, we investigated the incidence of injected vaccine in 1983 ~ 1988. Subjects and methods of investigation The survey using retrospective epidemiological casework survey method