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Ugi-4CC四组份缩合反应是基于异腈的MCR’s（多组份缩合反应）之中一类，它以异腈、羧酸、醛、胺为原料，可经一罐反应缩合生成由四种起始物共同组成的产物。此反应充分利用异腈的特性，通过使用不同的反应物，可用于合成不同结构骨架的系列化合物。本文合成了两种异腈，并进行了一系列Ugi反应以改进反应条件。
Ugi-4CC four-component condensation reaction is based on the isocyanide MCR’s (multi-component condensation reaction) among them, it isocyanurate, carboxylic acid, aldehyde, amine as raw material, Starting materials together constitute the product. This reaction takes full advantage of the isonitrile properties and can be used to synthesize a series of compounds with different structural backbones by using different reactants. In this paper, two kinds of isonitriles were synthesized and a series of Ugi reactions were carried out to improve the reaction conditions.