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目的：了解Ｇｉｌｂｅｒｔ病发病情况，辅助临床诊断Ｇｉｌｂｅｒｔ病，分析不同类型黄疸和健康人的血清胆红素构成。方法：ＨＰＬＣ法。结果：“遗传性黄疸”组血清胆红素与文献报道的Ｇｉｌｂｅｒｔ病表现基本一致而与其它类型黄疸和健康人有明显差别。结论：临床上常规采用的重氮法，因过高估计血清结合胆红素而对Ｇｉｌｂｅｒｔ病几乎没有诊断价值，采用ＨＰＬＣ法分析血清胆红素构成，可将Ｇｉｌｂｅｒｔ病与正常人、溶血性黄疸、肝胆疾病鉴别开。
Objective: To understand the incidence of Gilbert disease, clinical diagnosis of Gilbert disease, analysis of different types of jaundice and healthy people serum bilirubin composition. Method: HPLC method. Results: Serum bilirubin in hereditary jaundice group was basically consistent with Gilbert’s disease reported in the literature, which was significantly different from other types of jaundice and healthy people. CONCLUSION: Diazoxide, which is routinely used clinically, is of little diagnostic value for Gilbert disease due to overestimation of serum conjugated bilirubin. Serum bilirubin can be analyzed by HPLC to compare Gilbert’s disease with normal people, hemolytic jaundice Hepatobiliary disease identification open.