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目的对老年慢性阻塞性肺疾病(COPD)合并肺结核(PTB)的临床特点进行回顾性分析。方法 2006年7月-2012年7月本院呼吸内科收治的老年COPD并发肺结核患者48例,其中活动性PTB(A组)23例,陈旧性PTB(B组)25例,另选择同期住院COPD患者无结核(C组)26例。分析比较上述各组患者各临床相关指标以及住院时间、住院费用等。结果与C组相比,B组感染指标血沉(ESR)、C反应蛋白(CRP)较高,营养学指标血红蛋白(Hb)、白蛋白(ALB)和体重指数(BMI)较低,差异有统计学意义(P<0.05);而B组感染指标ESR、CRP高于A组,营养学指标Hb、ALB低于A组,差异有统计学意义(P<0.05);老年COPD合并PTB患者住院时间长、住院费用高。结论肺结核影响老年慢性阻塞性肺疾病的临床进程,主要表现为COPD合并PTB病情重以及营养状态较差、住院时间较长及住院费用高。
Objective To retrospectively analyze the clinical features of elderly patients with chronic obstructive pulmonary disease (COPD) and pulmonary tuberculosis (PTB). Methods From July 2006 to July 2012, 48 patients with elderly COPD and pulmonary tuberculosis admitted to our department of respiratory medicine were enrolled. Among them, 23 were active PTB (group A), 25 were old PTB (group B) Patients without tuberculosis (C group) in 26 cases. Analysis and comparison of the above-mentioned groups of patients with clinically relevant indicators and hospital stay, hospitalization costs. Results Compared with group C, the indexes of ESR and CRP in group B were higher than those in group C, and the indexes of nutrition such as hemoglobin, albumin (ALB) and body mass index (BMI) were lower than those in group C (P <0.05), while the indexes of ESR and CRP in group B were higher than those in group A, the indexes of nutrition Hb and ALB were lower than those in group A (P <0.05), and the length of stay in elderly COPD with PTB Long, expensive hospitalization. Conclusions Pulmonary tuberculosis affects the clinical course of chronic obstructive pulmonary disease in the elderly. The main symptoms of COPD with PTB are poor nutritional status, long hospital stay and high hospitalization costs.