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我们为了下列两个目的,进行了经气管给药后血、痰及肺组织中药物含量的测定: 1.观察经气管给药后,药物在体内吸收,移行的情况,提供临床治疗的参考; 2.通过分析不同给药途径对肺组织局部药物含量的影响,来阐明局部给药的优越性。一、实验材料和方法实验材料分二部分:一部分是以经气管给药的肺结核患者为对象(一般在测定期间均停止全身用药),在滴入不同浓度的不同药物后的一定时间内采血,以
We tested the blood, sputum and lung tissue contents after intratracheal administration for the following two purposes: 1. To observe the drug absorption and migration in the body after tracheal administration, and to provide a reference for clinical treatment; Through the analysis of different routes of administration on the local drug content of lung tissue, to clarify the superiority of local administration. First, the experimental materials and methods Experimental materials divided into two parts: one part is the tracheal administration of pulmonary tuberculosis patients as the object (usually during the measurement were stopped systemic medication), dripping different concentrations of different drugs within a certain time after blood, To