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对8例伴发糖尿病拟行择期妇科手术病人,观察硬膜阻滞下不同手术时点泌乳素(PRL)的动态变化,结果发现于切皮至术后次晨与术前比较呈显著性差异(P<0.05)。麻醉后30分钟PRL与术前比较则无明显差异(P>0.05);结论:在硬膜外阻滞下可抑制或减轻术中术后应激激素(多巴等)的释放,有助内稳态稳定。
Eight patients with concomitant diabetes mellitus undergoing gynecological surgery were enrolled in this study. The dynamic changes of prolactin (PRL) at different operative periods under epidural block were observed. The results showed that there was a significant difference between pre-operation and skin incision (P <0.05). At 30 minutes after anesthesia, there was no significant difference in PRL between the two groups (P> 0.05). CONCLUSION: The release of intraoperative and postoperative stress hormones (dopa and so on) can be suppressed or reduced under epidural block, Steady state.