作者报告８例十二指肠绒毛瘤，共切除１１个肿瘤。肿瘤位于球部２个，降部９个。８例中４例肿瘤癌变，癌变率５０％。通过低张气钡造影和纤维内窥镜检查可以得出诊断。术中切下整个肿瘤做冰冻切片检查，根据病变性质和局部情况，选择不同手术方式可收到良好治疗效果。因肿瘤局部切除有复发可能，故术后定期随访并做内窥镜检查是十分重要的。 The authors report 8 cases of duodenal choriocarcinoma, and a total of 11 tumors were removed. The tumors were located in two spheres and nine descending areas. Of the 8 cases, 4 cases had canceration and the canceration rate was 50%. Diagnosis can be made by low-level gas angiography and fiberoptic endoscopy. The whole tumor was cut off during surgery to perform frozen section examination. According to the nature of the lesion and local conditions, different surgical methods can be used to receive good therapeutic effects. Due to the possibility of recurrence of local resection of the tumor, it is very important that regular follow-up after surgery and endoscopy.