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目的通过分析2010—2012年乌鲁木齐市疑似预防接种异常反应(AEFI)监测数据和资料,为建立规范化疑似异常反应监测体系提供依据。方法收集乌鲁木齐市2010—2012年全国疑似AEFI网络报告系统的监测病例(1 086例),对疑似异常反应的分布情况及相关指标进行比较分析。结果 2010—2012年乌鲁木齐市疑似AEFI报告率分别为42.71/10万、62.79/10万、59.84/10万。一类疫苗和二类疫苗的疑似AEFI报告发生率差异有统计学意义。疑似AEFI涉及18种疫苗,各类疫苗AEFI报告率在2.95/10万~425.79/10万。0岁~、1岁~组的报告率占50%以上。结论建立和完善规范化的疑似AEFI信息监测系统,提高疑似AEFI报告的敏感性和利用率,规范监测的流程,加强业务人员的规范化操作,对于降低疑似AEFI的发生至关重要。
Objective To analyze the data of AEFI surveillance in Urumqi from 2010 to 2012 and provide evidences for establishing a standardized monitoring system of suspected abnormal reaction. Methods The surveillance cases (1 086 cases) of the national suspected AEFI network reporting system in Urumqi from 2010 to 2012 were collected, and the distribution of suspected anomalous reactions and related indicators were compared and analyzed. Results The reported rates of suspected AEFI in Urumqi from 2010 to 2012 were 42.71 / 100000, 62.79 / 100000 and 59.84 / 100000 respectively. The incidence of suspected AEFI reports for one type of vaccine and two types of vaccines was statistically different. Suspected AEFI involves 18 kinds of vaccines, various types of vaccine AEFI reported rate of 2.95 / 100000 ~ 425.79 / 100,000. 0 years old ~, 1 year old ~ group report rate of more than 50%. Conclusion Establishing and perfecting standardized AEFI information monitoring system, improving the sensitivity and utilization rate of suspected AEFI report, standardizing the monitoring process and strengthening the standardization of business personnel are very important to reduce the occurrence of suspected AEFI.