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目的探讨原始神经外胚层肿瘤(PNET)的临床特点和诊疗方法。方法回顾性分析中国医科大学附属第一医院收治的1例胸腺原始神经外胚层肿瘤的临床资料,分析其临床、病理及治疗的特点。结果经超声引导下穿刺取病理,行免疫组化,获得组织学证据,诊断为胸腺原始神经外胚层肿瘤(IV期)。结论 PNET属于高度恶性肿瘤,易发生远处转移,且预后差,因发病罕见,临床及病理医师对其认识不足,易造成误诊或漏诊。
Objective To investigate the clinical features and diagnosis and treatment of primitive neuroectodermal tumor (PNET). Methods The clinical data of 1 thymus primary neuroectodermal tumor treated in the First Affiliated Hospital of China Medical University were analyzed retrospectively. The clinical, pathological and therapeutic characteristics were analyzed. Results Ultrasound guided puncture pathology, immunohistochemistry, histological evidence, the diagnosis of thymus primitive neuroectodermal tumors (IV). Conclusions PNET is a highly malignant tumor, prone to distant metastasis, and its prognosis is poor. Because of its rare onset, clinicians and pathologists do not know enough about it, which may lead to misdiagnosis or missed diagnosis.