大麻素受体 (ＣＢ)刺激物减少疼痛刺激的反应 ,已有大量证据表明ＣＢ 1受体在抗感受伤害中发挥作用 ,然而位于中枢神经系统之外的ＣＢ 2受体在产生抗感受伤害中的作用 ,还不明了。通过使用ＡＭ 12 4 1(一种选择性ＣＢ 2受体的激动剂 ) ,我们发现ＣＢ 2大麻素受体对热刺激的伤害 The response of cannabinoid receptor (CB) stimulators to the reduction of painful stimuli has been extensively supported by the evidence that CB 1 receptors play a role in anti-nociception, whereas CB 2 receptors located outside the central nervous system contribute to anti-nociception The role is not clear. Using AM 12 4 1, an agonist of a selective CB 2 receptor, we found that CB 2 cannabinoid receptors harmed thermal stimuli