某些皮肤病如黑棘皮病、持久性回状红斑、获得型鱼鳞病等可以预示合并内脏恶性肿瘤已早为皮肤病学界所熟知.但这些皮肤病却很少能直接提示病人患何种特殊型的恶性肿瘤.现介绍一种少见的皮肤病——坏死松解性游走性红斑(necrolytic migratory erythema, NME)其皮疹特殊,而且几乎都伴发于胰岛α细胞瘤.患者常因发生皮疹而先来皮肤科就诊,继而再查出胰腺肿瘤.鉴于皮疹是最易被检查的体征,因而认识和了解作为胰岛α细胞瘤特有的皮肤症状,将为及时发现隐藏在体内的胰腺肿瘤提供可靠的证据,以使患者获得早期根治的机会. Some dermatological diseases such as acanthosis nigricans, persistent retrolental erythema, ichthyosis and other can predict the merger of visceral malignancies has long been known to dermatology, but these skin diseases are rarely able to directly prompt the patient what kind of special Type of malignant tumor is now introduced a rare skin disease - necrotic migratory erythema (necrolytic migratory erythema, NME) its rash is special, and almost all associated with pancreatic islet cell tumor patients often due to rash And dermatology clinic first, and then found the pancreatic tumor.Because the rash is the most easily inspected signs, and thus know and understand as pancreatic α-cell tumors unique to the skin symptoms, will promptly find hidden in the body of pancreatic tumors to provide reliable Of evidence to give patients early chance of cure.