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为确定直肠癌治疗后长期生存相关因素,对545例直肠癌患者采用单纯手术或综合治疗后生存5年以上者187例,按11种因素进行分析。结果表明,5年生存率与肿瘤大小、肿瘤侵犯肠管周长范围、病变大体类型、淋巴结转移、临床分期和治疗方法有非常显著相关性(P<0.005),与年龄、组织学分类和病变部位有显著相关性(P<0.05),与性别和病程关系不大(P>0.05)。我们认为提高直肠癌治疗后长期生存率,应从上述相关因素着手,综合治疗,尤其手术+术前放疗+术后化疗疗效最佳。
In order to determine the long-term survival related factors of rectal cancer after treatment, 545 cases of rectal cancer patients who had survived more than 5 years after surgery or comprehensive treatment were included. Among the 187 cases, 11 factors were analyzed. The results showed that the 5-year survival rate was significantly correlated with the tumor size, range of tumor invasion gut perimeter, gross lesion type, lymph node metastasis, clinical stage, and treatment methods (P < 0.005), with age, histological classification and The lesions were significantly correlated (P<0.05), and had little relationship with gender and course (P>0.05). We believe that to improve the long-term survival rate after treatment of rectal cancer, we should start from the above-mentioned related factors, comprehensive treatment, especially surgery + preoperative radiotherapy + postoperative chemotherapy the best effect.