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妊娠期肝病罕见(<0.1%)。其可分为三类:(1)妊娠特有的肝病;(2)妊娠前已有的肝病;(3)妊娠期新出现的肝病。本综述以第一类为主。妊娠肝内胆汁郁积(ICP)流行病学ICP 似乎有遗传性。其发生率在大多数国家为1/1000~10000次分娩,世界范围内为0.5~1%。在亚洲人及黑人中罕见。
Gestational liver disease is uncommon (<0.1%). It can be divided into three categories: (1) pregnancy-specific liver disease; (2) pre-pregnancy existing liver disease; (3) new-onset liver disease during pregnancy. This review focuses on the first category. Intrahepatic cholestasis of pregnancy (ICP) Epidemiology ICP seems to be hereditary. Its incidence is in the majority of countries for 1/1000 to 10000 births worldwide 0.5 to 1%. Rare in Asians and blacks.