利用１５３Ｓｍ－ＥＤＴＭＰ对骨转移癌患者进行内照射治疗，是近几年兴起的一种新疗法。它不仅可达到控制肿瘤、有效缓解骨痛的目的，而且由于其是针对病灶部位进行靶治疗，所以对周围正常组织伤害少。目前这一疗法在临床上的应用及其主要毒副作用正日益受到临床医师们的关注 The use of 153Sm-EDTMP in patients with bone metastases for internal irradiation treatment, is a rise in recent years, a new therapy. It not only achieves the purpose of controlling the tumor and effectively alleviating the bone pain, but also harms the surrounding normal tissue as it is targeted for the lesion site. At present, the clinical application of this therapy and its main toxicities and side effects are increasingly attracting the attention of clinicians