慢性疲劳综合征(Chronic Fatigue Syndrome,CFS)是近十年来才引起医学家们注意的一种新疾病。国外对本病研究得比较多,且取得了重大进展。现将有关资料综述如下。一、命名与发生率 CFS是一种病因未明的疾病,1988年5月美国疾病控制中心才正式将本病列为一种综合征,以往也称Akureyris病、流行性神经肌无力综合征、冰岛病、神经衰弱、良性或流行性肌痛性脑炎、皇室闲病、慢性单核细胞症、病毒感染后无力综合征、感染后神经肌肉无力症、慢性EB病毒综合征等。CFS的发生率目前尚无详细报道,Manu等报道以慢性疲劳症状就诊占内科门诊的4％,占全部门诊人数的2.6％。本病女性多于男性,且以中年妇女易患此病。二、病因 Chronic Fatigue Syndrome (CFS) is a new disease that has drawn the attention of medical scientists in the last ten years. Foreign study of this disease more, and made significant progress. The relevant information is summarized below. First, the name and incidence CFS is a disease of unknown etiology, in May 1988 the United States Centers for Disease Control formally the disease as a syndrome, formerly known as Akureyris disease, epidemic neuromuscular syndrome, Iceland Disease, neurasthenia, benign or epidemic myalgic encephalitis, royal cholelithiasis, chronic monocytic disease, weakness syndrome after viral infection, post-infection neuromuscularosis, chronic Epstein-Barr virus syndrome and the like. The incidence of CFS is not yet reported in detail, Manu et al reported that chronic fatigue symptoms accounted for 4% of outpatient clinic, accounting for 2.6% of all out-patient. The disease more women than men, and middle-aged women predispose to the disease. Second, the cause