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目的:探讨他克莫司治疗特发性膜性肾病效果。方法:将该院接受特发性膜性肾病检查的60例患者分为两组,根据治疗方法不同,分为他克莫司组和LEF组,观察两组患者的各项指标以及不良反应情况。结果:LEF治疗组的治疗效果明显落后于他克莫司治疗组(P<0.05)。结论:他克莫司治疗特发性膜性肾病效果明显,药品副作用小,安全性较高,值得临床推广使用。
Objective: To investigate the effect of tacrolimus in the treatment of idiopathic membranous nephropathy. Methods: 60 patients with idiopathic membranous nephropathy were divided into two groups. According to the different treatment methods, the patients were divided into two groups: the tacrolimus group and the LEF group. The indexes and the adverse reactions of the two groups were observed . Results: The therapeutic effect of LEF treatment group lagged behind that of tacrolimus treatment group (P <0.05). Conclusion: Tacrolimus is effective in treating idiopathic membranous nephropathy with less side effects and higher safety. It is worthy of clinical promotion.