论文部分内容阅读
目的 为了解性乱人群不典型皮损中及无皮损的生殖道分泌物中 2型单纯疱疹病毒 (HSV2 )的感染情况。方法 在HSV2 高度保守的基因区设计一对引物 ,利用聚合酶链反应 ,对合肥地区 62 0例性乱者作HSV2 DNA检测。结果 3 75例不典型皮损的性乱人群中 ,14 1例检出HSV2 DNA ,阳性率为 3 7.6% ,其中男性占 3 3 .6% ,女性占 47.7%。男女之间差异显著 (P <0 .0 5 )。无皮损性乱人群 2 45例 ,60例检出HSV2 DNA ,占 2 4.5 % ,其中男性占 2 2 .2 % ,女性占 2 9.7%。结论 本地区性乱人群中HSV2 有较高的感染率 ,不典型皮损区HSV2 DNA阳性检出率高于无皮损的生殖道分泌物 ,女性感染率高于男性。
Objective To understand the infection of herpes simplex virus type 2 (HSV2) in atypical lesions and non-epithelial genital secretions in sexual disorders. Methods A pair of primers was designed in the highly conserved region of HSV2. HSV2 DNA was detected by polymerase chain reaction in 62 0 cases in Hefei area. Results Among 3 75 cases of atypical lesions, HSV2 DNA was detected in 14 1 cases, with a positive rate of 37.6%, of which 33.6% were male and 47.7% were female. The difference between men and women was significant (P <0.05). There were 2 45 cases of non-dermal injury, 60 cases of HSV2 DNA were detected, accounting for 4.5%, of which 22.2% were men and 27.7% were women. Conclusions The prevalence of HSV2 infection in the local population is higher than that in the non-skin lesions. The prevalence of HSV2 DNA in the atypical lesions is higher than that in the non-skin lesions.