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目的探讨小剂量雌激素在绝经后妇女泌尿系感染反复发作患者中的应用价值。方法 98例绝经后妇女泌尿系感染反复发作患者随机分为观察组和对照组,各49例,给予观察组患者小剂量雌三醇软膏治疗,给予对照组患者抗生素治疗,并对两组患者治疗后雌二醇E2水平、阴道健康评分、阴道pH值及治疗总有效率进行对比。结果观察组患者和对照组患者治疗总有效率比较,观察组总有效率为93.88%,对照组为69.39%,差异具有统计学意义(P<0.05),观察组患者雌二醇E2水平、阴道健康评分、阴道pH值均明显优于对照组(P<0.05)。结论将小剂量雌激素应用于绝经后妇女泌尿系感染反复发作患者的治疗中具有较高的价值,临床效果显著,值得推广和应用。
Objective To investigate the value of low-dose estrogen in patients with recurrent urinary tract infection in postmenopausal women. Methods 98 cases of post-menopausal women with recurrent urinary tract infection were randomly divided into observation group and control group, 49 cases in each group. Patients in observation group were treated with low-dose estriol ointment. Patients in control group were given antibiotics. Estradiol E2 level, vaginal health score, vaginal pH value and the total effective rate of treatment were compared. Results Compared with the control group, the total effective rate was 93.88% in the observation group and 69.39% in the control group, the difference was statistically significant (P <0.05), the estradiol E2 level in the observation group, vaginal Health score, vaginal pH value were significantly better than the control group (P <0.05). Conclusion The application of low-dose estrogen in the treatment of recurrent urinary tract infection in post-menopausal women is of high value, and the clinical effect is significant, which is worthy of popularization and application.