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目的了解定州市慢性心力衰竭患者应用β-受体阻滞剂的情况。方法对定州市3所医院住院的慢性心力衰竭患者病历进行回顾性调查分析。结果β-受体阻滞剂2006-2009年在慢性心力衰竭患者中使用率分别为18.78%、27.34%、43.90%和53.81%,总使用率为37.98%,有逐年增高趋势,医生在诊治慢性心力衰竭中,β-受体阻滞剂的无服药医嘱率有逐年下降趋势,心功能Ⅳ级患者β-受体阻滞剂长期服药率明显低于心功能Ⅲ级和Ⅱ级患者(P<0.05),服药过程中停药率均明显高于心功能Ⅲ级和Ⅱ级患者(P<0.05)。结论定州市慢性心力衰竭患者应用β-受体阻滞剂治疗比例较低,虽有逐年增加趋势,但尚需进一步加强。
Objective To understand the application of β-blockers in patients with chronic heart failure in Dingzhou. Methods Retrospective analysis of medical records of patients with chronic heart failure admitted to 3 hospitals in Dingzhou City. Results β-blockers used in patients with chronic heart failure in 2006-2009 were 18.78%, 27.34%, 43.90% and 53.81%, respectively, the total utilization rate was 37.98%, with a trend of increasing year by year. Doctors in the treatment of chronic In heart failure, the rate of non-medication prescription of β-blockers decreased year by year. The long-term rate of β-blockers in patients with heart function Ⅳ levels was significantly lower than those in patients with grade Ⅲ and Ⅱ heart dysfunction (P < 0.05). The withdrawal rates during medication were significantly higher than those in patients with grade Ⅲ and Ⅱ cardiac function (P <0.05). Conclusion The treatment of chronic heart failure in Dingzhou patients with β-blockers a lower proportion, although the trend of increasing year by year, but still need to be further strengthened.