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目的:探究药剂科管理对临床抗生素应用合理性的影响。方法:自2015年1月起调整药剂科管理方案,提高药剂科工作人员专业水平,控制抗生素采购管理,改善抗生素滥用现状,纠正抗生素不合理应用现象,深入临床工作进行指导,加强对临床抗生素的管理,随机从各临床科室抽取2015年处方200张作为观察组,并抽取2014年处方200张作为对照组,比较加强管理前后的抗生素应用率、抗生素不合理应用率及处方金额。结果:加强药剂科管理后,抗生素应用率从65.5%降为了32.0%,抗生素不合理应用率从14.5%降为了1.6%,处方药物金额从(94.5±21.7)元降为了(63.6±11.2)元,差异均显著(P<0.05)。结论:加强药剂科管理,能够有效促进临床抗生素的合理应用,降低抗生素的应用率及不合理应用率,同时也减少了患者的医疗开支,提高了整体医疗质量。
Objective: To explore the influence of pharmacy management on the rationality of clinical antibiotics. Methods: From January 2015, the pharmacy management plan was adjusted to improve the professional level of pharmacy staff, to control the procurement of antibiotics, to improve the current status of antibiotic abuse, to correct the unreasonable application of antibiotics, to guide in-depth clinical work and to strengthen the supervision of clinical antibiotics Management randomly selected 200 prescriptions in 2015 from all clinical departments as the observation group, and took 200 prescriptions in 2014 as the control group to compare the application rate of antibiotics before and after administration, the unreasonable application rate of antibiotics and the prescription amount. Results: The rate of antibiotics application dropped from 65.5% to 32.0% and that of antibiotics from 14.5% to 1.6%. The amount of prescription drugs dropped from (94.5 ± 21.7) yuan to (63.6 ± 11.2) yuan , The differences were significant (P <0.05). Conclusion: Strengthening the management of pharmacy department can effectively promote the rational use of clinical antibiotics, reduce the application rate of antibiotics and unreasonable application rate, meanwhile reduce the patients’ medical expenses and improve the overall medical quality.