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近日,血液中心HLA实验室发现并提交的3个人类白细胞抗原(HLA)新等位基因已被WHO(世界卫生组织)HLA系统因子命名委员会正式命名为HLA-B*510108、HLA-B*5527和HLA-B*5413,新基因序列即将发表在《组织抗原》、《人类免疫学》、《国际免疫遗传学杂志》等国际著名刊物上。这次发现的三个新等位基因是我中心对30000余份造血干细胞捐献者血样进行DNA水平的HLA分型时发现的。
Recently, three new human leukocyte antigen (HLA) alleles that HLA laboratories at the Hematology Center discovered and submitted have been officially named as HLA-B * 510108 by HLA (World Health Organization) HLA System Factor Nomenclature Committee, HLA-B * 5527 And HLA-B * 5413, the new gene sequences will be published in international famous journals such as Tissue Antigen, Human Immunology, and International Journal of Immunogenetics. The three new alleles found at this time were found at the DNA level HLA typing of blood samples of more than 30,000 hematopoietic stem cell donors from our center.