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为提高对慢型、亚急型、急型克山病的治疗效果。探讨亚急型、急型克山病的早期诊断,我们于79年夏、秋季在云南省大理县对部分慢型、亚急型、急型克山病患者用Regitine加适量葡萄糖液静脉滴注观察。现小结于下: 一、资料来源: 所有病历全部为大理县农村病区来县医院就医者。共观察15例,其性别、年令、心功见附表。二、具体措施:Regitine 10毫克,维生素丙2.5克,加适量葡萄糖液。总液体量:20—25毫升/公斤体重,给液速度8毫升/公斤体重小时,Regitine滴入速度:0.05毫克/分。浮肿明显者加入适当剂量利尿剂与钾盐。给药前收集病史,记录自觉症状、血压、心率及阳性体征、排尿、描记九个导联心电图。滴注开始后经常观察血压、心率、自觉症状及阳性体征。此后每30分钟记录一次。滴注结束时全面检查记录一次。心电图有改变者,定时观察,直至恢复到用药前的心电图止。记录滴注开始后12小时尿量。三、观察结果: 7名慢克除例107例外,滴注开始10分钟后,收缩压升高10～20毫米汞柱,心率增加10—20次/分。患儿无不适感,气短减轻,排尿增多。心电图2例(107、149)V_1PTF加深,2例(109、116)PV_1电压增高,主要是PV_1前半部分增高,例148PV_1电压有所降低。ST—T改变:除例116用药后STV_3明显下降外,余同前无明显差异。 6例亚急型克山病中例(114、165、
To improve the slow, sub-acute, acute Keshan disease treatment. To investigate the early diagnosis of subacute and acute Keshan disease, we used Regitine plus appropriate glucose intravenous infusion in part of patients with chronic, subacute and acute Keshan disease in Dali County, Yunnan Province in the summer of 1979. Observed. Now summarized in the following: First, Source: All medical records for Dali County, rural ward to the county hospital for medical treatment. A total of 15 cases were observed, the gender, year, heart see Schedule. Second, the specific measures: Regitine 10 mg, 2.5 grams of vitamin C, add appropriate glucose solution. Total fluid volume: 20-25 ml / kg body weight, fluid speed 8 ml / kg body weight hour, Regitine infusion rate: 0.05 mg / min. Edema obvious by adding the appropriate dose of diuretics and potassium. Collect the medical history before administration, record the symptoms, blood pressure, heart rate and positive signs, urination, tracing the nine lead ECG. After the start of infusion often observed blood pressure, heart rate, symptoms and positive signs. Record every 30 minutes thereafter. Completely record the record once at the end of the instillation. ECG changes, regular observation, until the return to the ECG before medication. Record the amount of urine output 12 hours after instillation. Third, the observation results: 7 cases of chronic exception except cases 107, 10 minutes after the start of infusion, systolic blood pressure increased 10 to 20 mm Hg, heart rate increased 10-20 beats / min. No discomfort in children, shortness of breath, increased urination. Two cases of electrocardiogram (107,149) V_1PTF deepened, 2 cases (109,116) PV_1 voltage increased, mainly in the first half of PV_1 increased, 148PV_1 voltage decreased. ST-T changes: In addition to the 116 cases of STV_3 significantly decreased after treatment, with the former no significant difference. 6 cases of subacute Keshan disease (114,165,