雌、孕激素联合周期治疗与发生子宫内膜癌的危险性之间的关系尚不确定,为此进行病例对照研究。1985～1991年美国华盛顿州三座城市中1 154例45～74岁,有组织学证实的子宫内膜癌的妇女,其中100例已经死亡,63例的医生拒绝提供资料,158例拒绝参与研究,余832例参加研究。同时,在该三座城市中根据电话号码招募对照组。2 620例在年龄及居住地等方面符合条件者中1 114例做为对 The relationship between estrogen and progesterone combined with periodic therapy and the risk of developing endometrial cancer remains uncertain. Case-control studies were conducted for this purpose. Between 1985 and 1991, 1,154 women aged 45-74 years with histologically confirmed endometrial cancer in three of Washington’s three cities of the United States, of whom 100 died, 63 refused to provide information and 158 refused to participate in the study , More than 832 cases participated in the study. At the same time, control groups were recruited in the three cities by phone number. A total of 1 620 cases of 2 620 cases matched with age and place of residence were considered as correct