论文部分内容阅读
目的对比局部浸润麻醉和硬膜外麻醉在乳腺良性肿瘤切除术中的效果。方法 50例乳腺良性肿瘤切除术患者,随机分为观察组和对照组,各25例。对照组患者实施硬膜外麻醉,观察组患者实施局部浸润麻醉。对比分析两组患者的免疫功能变化。结果对照组患者在麻醉后30、60 min和麻醉前相比,CD4+水平有显著升高,自然杀伤细胞(NK)水平有显著下降(P<0.05);对照组患者在麻醉后和麻醉前相比,免疫球蛋白G(Ig G)、免疫球蛋白A(Ig A)、免疫球蛋白M(Ig M)浓度显著下降(P<0.05);观察组麻醉后和麻醉前相比,Ig G、Ig A、Ig M浓度差异无统计学意义(P>0.05);麻醉后30 min对照组Ig G、Ig A、Ig M浓度分别为(9.24±4.23)、(1.42±0.75)、(1.00±0.21)g/L,和观察组相比显著下降(P<0.05)。结论在乳腺良性肿瘤切除术中,对患者实施局部浸润麻醉可以减少对患者免疫功能的影响,值得推广。
Objective To compare the effect of local infiltration anesthesia and epidural anesthesia in benign breast tumor resection. Methods Fifty patients with benign breast tumor were randomly divided into observation group and control group, with 25 cases in each group. Patients in the control group underwent epidural anesthesia and patients in the observation group received local anesthesia. Comparative analysis of two groups of patients with immune function changes. Results Compared with before anesthesia, the level of CD4 + and the level of natural killer (NK) in control group were significantly decreased at 30 and 60 minutes after anesthesia (P <0.05). In control group, the level of CD4 + (P <0.05). The levels of Ig G, Ig A and Ig M in the observation group were significantly lower than those before the anesthesia The Ig G, Ig A and Ig M concentrations of control group were (9.24 ± 4.23), (1.42 ± 0.75), (1.00 ± 0.21 ) g / L, significantly decreased compared with the observation group (P <0.05). Conclusions In the treatment of benign breast tumors, local infiltration anesthesia can reduce the impact of patients with immune function, which is worth promoting.