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目的研究 B 细胞非霍奇金淋巴瘤(B-NHL)患者外周血单个核细胞(PBMNC)Blys 表达情况,探讨 Blys 的转录水平与 B-NHL 的关系,分析 Blys 在 B-NHL 发病中的作用。方法应用实时荧光定量 PCR 法(RFQ-PCR)检测B-NHL(31例)患者 PBMNC Blys mRNA 的表达水平,以健康献血员(30例)作为对照,并对 B-NHL 不同分型及化疗
Objective To investigate the expression of Blys in peripheral blood mononuclear cells (PBMNC) from patients with B-cell non-Hodgkin’s lymphoma (B-NHL) and to explore the relationship between Blys transcription and B-NHL and the role of Blys in the pathogenesis of B-NHL . Methods The expression of Blys mRNA in PBMNC was detected by real-time quantitative PCR (RFQ-PCR) in 30 B-NHL patients. The healthy donors (30 cases)