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目的观察复方丹参针联合纳洛酮治疗新生儿缺氧缺血性脑病(HIE)的疗效。方法103例HIE患儿随机分成两组,治疗组56例,对照组47例,除进行相同的常规治疗外,治疗组给予纳洛酮静滴,连用5~7 d,复方丹参针静滴,连用10~15 d,观察患儿临床症状的变化。并随访1年,观察神经系统后遗症的发生率。结果治疗组患儿临床症状明显改善,神经系统后遗症发生率低。结论复方丹参针联合纳洛酮治疗HIE疗效显著。
Objective To observe the curative effect of compound salvia miltiorrhiza combined with naloxone on neonatal hypoxic-ischemic encephalopathy (HIE). Methods A total of 103 children with HIE were randomly divided into two groups: 56 cases in the treatment group and 47 cases in the control group. In addition to the same routine treatment, the treatment group received intravenous naloxone for 5-7 days, Used 10 ~ 15 d, observation of clinical changes in children. Followed up for 1 year, observed the incidence of nervous system sequelae. Results The clinical symptoms of children in the treatment group were significantly improved, and the incidence of nervous system sequelae was low. Conclusion The compound salvia miltiorrhiza combined with naloxone is effective in treating HIE.