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目的比较中年与老年女性卵巢肿瘤的临床特点、治疗及预后的差异,并分析预后相关因素。方法回顾性分析辽河油田中心医院诊治的70例卵巢恶性肿瘤患者,将其分为中年组(45～60岁)40例、老年组(≥65岁)30例,对其临床症状、术后残瘤灶大小、化疗及预后分别进行对比分析,并进行预后相关因素分析。结果中、老年女性3年生存率分别为72.3%、60.5%。单因素分析显示青、老年女性3年生存率差异有统计学意义。行最佳减瘤术及完成化疗者,中年组所占比例显著较老年组多(分别为86.5%vs.41.3%,70%vs.49%)。结论中年女性预后较老年女性好,卵巢癌预后与年龄有关,但年龄不是预后的重要因素。残瘤灶大小及化疗是影响预后的独立因素。
Objective To compare the clinical features, treatment and prognosis of middle-aged and elderly women with ovarian tumors and to analyze the prognostic factors. Methods A retrospective analysis of 70 patients with ovarian cancer diagnosed and treated in Central Hospital of Liaohe Oilfield was divided into 40 cases in the middle-aged group (45-60 years old) and 30 cases in the elderly group (≥65 years old). The clinical symptoms, The size of the residual tumor, chemotherapy and prognosis were compared and analyzed, and prognostic factors. Results, the elderly women 3-year survival rates were 72.3%, 60.5%. Univariate analysis showed that the difference of 3-year survival rate was statistically significant between young and old women. The patients who received the best cytoreductive surgery and completed chemotherapy were significantly more likely to be in the middle-aged group than in the elderly group (86.5% vs. 41.3%, 70% vs. 49%, respectively). Conclusion The prognosis of middle-aged women is better than that of the elderly. The prognosis of ovarian cancer is related to age. However, age is not an important prognostic factor. Tumor size and chemotherapy is an independent prognostic factor.