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Objective To explore whether docetaxel-resistant cells(MCF-7/Doc)and doxorubicin-resistant cells(MCF-7/ADM)can secrete Exosomes and their potential role in cell-cell drug-resistance transfer.Methods Exosomes were extracted from the cell culture supernatants of MCF-7/Doc and MCF-7/ADM cells by fractionation ultracentrifugation,and were identified by transmission
Objective To explore whether docetaxel-resistant cells (MCF-7 / Doc) and doxorubicin-resistant cells (MCF-7 / ADM) can be scoped Exosomes and their potential role in cell-cell drug- resistance transfer. Methods Exosomes were extracted from the cell culture supernatants of MCF-7 / Doc and MCF-7 / ADM cells by fractionation ultracentrifugation, and were identified by transmission