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目的:观察比较七氟烷与氯胺酮麻醉诱导用于患儿全身麻醉的效果。方法:90例手术患儿随机分为两组。七氟烷组采用七氟烷面罩吸入麻醉诱导,氯胺酮组患儿予氯胺酮静注麻醉诱导。监测记录两组患儿麻醉过程中的平均动脉压(MAP)、心率(HR)、血氧饱和度(S_pO_2),以及麻醉诱导时间、苏醒时间、定向力恢复时间、出手术室时间以及并发症发生情况。结果:麻醉后与切皮时,两组患儿的MAP、HR均较入室时均明显升高(P<0.05),而氯胺酮组切皮时的MAP、HR明显高于七氟烷组(P<0.05)。七氟烷组患儿的诱导时间、苏醒时间、手术时间、定向力恢复时间及出手术室时间均明显短于氯胺酮组(P<0.01);术后并发症的发生率明显低于氯胺酮组(P<0.01)。结论:七氟烷麻醉诱导在患儿全身麻醉中应用效果良好,安全性高,值得临床推广应用。
Objective: To observe and compare the effects of sevoflurane and ketamine anesthesia induction on general anesthesia in children. Methods: Ninety children with surgery were randomly divided into two groups. The sevoflurane group was induced by sevoflurane mask inhalation anesthesia, ketamine group was given ketamine intravenous anesthesia induction. The mean arterial pressure (MAP), heart rate (HR), oxygen saturation (S_pO_2) during anesthesia and anesthesia induction time, recovery time, recovery time of orientational force, time of operation room and complication What happened? Results: After anesthesia and skin incision, the MAP and HR in both groups were significantly higher than those in the control group (P <0.05), while the MAP and HR in the ketamine group were significantly higher than those in the sevoflurane group <0.05). The induction time, recovery time, operation time, recovery time of orientational force and operating room time were significantly shorter in sevoflurane group than in ketamine group (P <0.01). The incidence of postoperative complications was significantly lower than that of ketamine group P <0.01). Conclusion: Sevoflurane induction of anesthesia in children with good effect of general anesthesia, high safety, deserved clinical application.