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祖国医学用苦参(Sophora flavescens Ait.)治疗风疹、湿热痢疾、黄疸和杀虫、利水等。本文报道苦参一个新的研究方面——平喘。苦参煎剂15g/kg、总生物碱和结晶碱100～200mg/kg,灌胃给药,63只组胺性哮喘豚鼠平喘率第一小时达95%,第六小时仍在80%以上,水对照组20只豚鼠平喘率为15%左右,统计比较差异非常显著(P<0.001)。氨茶碱组29只动物,药量为75～100mg/kg,第一小时平喘率也在90%以上.但第六小时仅有55%。苦参平喘强度与氨茶碱相似,但维持时间较长。苦参的平喘作用已在临床证实,经500余例支气管哮喘和喘息型慢性气管炎患者治疗统计,有效率为86%。
The Chinese medicine Sophora flavescens Ait. treats rubella, hot and humid diarrhea, jaundice, insecticides, and water. This article reports a new research aspect of Sophora flavescens - asthma. Sophora flavescens decoction 15g/kg, total alkaloids and crystalline base 100 ~ 200mg/kg, intragastric administration, the asthmatic rate of 63 histamine asthma guinea pigs reached 95% for the first hour, and still more than 80% in the sixth hour The asthma control rate of 20 guinea pigs in the water control group was about 15%, and the statistical difference was very significant (P<0.001). Aminophylline group 29 animals, the dose of 75 ~ 100mg/kg, the first hour asthma rate is also more than 90%. But the sixth hour is only 55%. The antiasthmatic intensity of Sophora flavescens is similar to that of aminophylline, but it takes a long time to maintain. The antiasthmatic effect of Sophora flavescens has been clinically confirmed. After more than 500 cases of bronchial asthma and asthmatic chronic bronchitis were treated, the effective rate was 86%.