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化脑是小儿时期多见而又严重的疾病。早期诊断、彻底治疗,密切关系着病儿预后。临床症状、体征、脑脊液异常、为诊断重要依据。必须掌握各年龄阶段的特点,尤其是3个月以下的幼婴、早期病例,以及经过抗菌素不彻底治疗的非典型表现,并尽可能明确病原。治疗中仅着重谈及如何合理选用抗菌素问题,要对病原菌敏感,能透过血脑屏障,剂量充足,疗程适当,并注意用药途径。急性期静脉分次给药,必要时鞘内或脑室内注射。
Brain is more common in childhood and severe disease. Early diagnosis, thorough treatment, closely related to the prognosis of sick children. Clinical symptoms, signs, abnormal cerebrospinal fluid, an important basis for the diagnosis. The characteristics of all ages must be mastered, especially for young infants less than 3 months old, early cases, and atypical manifestations of inadequate antibiotic treatment, with a clear pathogen identification. Treatment focuses only on how to properly select antibiotics, to be sensitive to pathogens, through the blood-brain barrier, adequate dose, appropriate treatment, and pay attention to the route of administration. Acute intravenous administration, if necessary, intrathecal or intraventricular injection.