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COVID-19在全球范围的爆发流行，给全世界人民的生产生活造成了严重的影响。COVID-19的传播速度快、感染率强、死亡率高，其感染宿主的机制仍不清楚。T淋巴细胞是人体抵御病毒感染的重要防线，对宿主清除病毒免受病毒感染至关重要。文章回顾了已有冠状病毒感染疾病相关研究结果，就T细胞在冠状病毒感染中的作用与变化及对新冠肺炎的预后的预测价值综述。“,”The global outbreak of coronavirus disease 2019(COVID-19)has seriously affected the lives of people around the world. The COVID-19 is high infectious with high mortality. The mechanism by which COVID-19 infects the host remains unclear. T lymphocytes are one of important parts of the body's defense against viral infections, which are essential to eliminate viruses. The role of T lymphocytes in coronavirus related disease and predicted outcome was reviewed based on established research.