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连续血细胞流滤是近年来治疗某些血液病的一种重要方法。应用血细胞分离器,在不同转速离心下按血细胞比重,分别收集血细胞及血浆。把所需的血液成分留下,剩下其余成分回输供体。本文报告应用国产材料研制LXF-1连续血细胞分离器获得成功。仪器达到原订指标要求,浓集白细胞数为4.05±1.6倍(范围1.78～6.94),白细胞产额增加数23.6±11.99(范围8.75～47.2％)。收集白细胞总数达4.6×10~9,与国外同类产品水平接近。流滤白细胞活性(台盼兰染料排斥试验),血细胞形态及分类旨正常,肝功及心电图检查无特异。实验后的动物血相恢复良好。被认为是安全可靠的一种血细胞分离方法,可直接应用临床。
Continuous hemofiltration is an important method of treating certain blood diseases in recent years. Application of blood cell separator, centrifuged at different speeds according to the proportion of blood cells were collected blood cells and plasma. Leave the desired blood composition, leaving the remaining ingredients back to the donor. This paper reports the application of domestic materials developed LXF-1 continuous hemolysis cell success. The instrument reached the original target requirements, the concentration of leukocytes 4.05 ± 1.6 times (range 1.78 ~ 6.94), white blood cell yield increased 23.6 ± 11.99 (range 8.75 ~ 47.2%). The total number of white blood cells collected was 4.6 × 10 ~ 9, close to the level of similar foreign products. Flow cytometry leukocyte activity (trypan blue dye rejection test), normal blood cell morphology and classification, liver function and ECG no specific. After the experiment the blood recovered well. Is considered to be a safe and reliable method of blood cell separation can be directly applied clinical.