本文对九个酚醛及酚酮类化合物的Dakin反应进行了研究。由于避免了过度的氧化和副反应,所以产率较文献报道的60～80％要高,可达81～96％。其中,2-甲酰基雌酚酮和4-甲酰基雌酚酮的Dakin反应尚未见报道,产率几乎是计算量的。采用本文的方法,可将Dakin反应由通常的甲酰基或乙酰基成功地扩展应用到含丙酰基的酚酮。 In this paper, Dakin reaction of nine phenols and phenolic ketones was studied. As to avoid excessive oxidation and side reactions, so the yield was higher than the reported 60 to 80%, up to 81 to 96%. Among them, the Dakin reaction of 2-formyl estrone and 4-formyl estrone has not been reported, and the yield is almost calculated. Using the method herein, the Dakin reaction can be successfully extended from the usual formyl or acetyl groups to propionyl-containing phenols.