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本文报道了我院新生儿病房1988年1月～1989年12月收治新生儿坏死性小肠结肠炎(NEC)88例,其中新生儿缺氧缺血性脑病(HIE)并发NEC 27例,占同期HIE病例的30.45％,占HIE病例数的16％。近年来NEC的病发有呈渐趋增加或相对增多的趋势。因此,本病发病因素应引起重视。本文27例病人中,25例以HIE入院,1例为RDS,1例为败血症合并HIE住院。经临床治疗,痊愈16例,死亡6例。5例家长放弃治疗,病死率为22％。本文提出加强围产保健,降低新生儿窒息发病率是预防本病的关键;并对围产期严重缺氧小儿应延长开奶时间。
This article reports 88 cases of neonatal necrotizing enterocolitis (NEC) admitted to neonatal wards in our hospital from January 1988 to December 1989. Among them, 27 cases of neonatal hypoxic ischemic encephalopathy (NIE) complicated with NEC occurred in the same period 30.45% of HIE cases, accounting for 16% of HIE cases. In recent years, the incidence of NEC showed a gradual increase or relative increase in the trend. Therefore, the incidence of the disease should pay attention to factors. Of the 27 patients in this study, 25 were hospitalized with HIE, 1 was RDS, and 1 was hospitalized for sepsis with HIE. After clinical treatment, 16 cases were cured and 6 died. Five parents gave up treatment, the fatality rate was 22%. This article proposes to strengthen the perinatal health care, reduce the incidence of neonatal asphyxia is the key to preventing this disease; and perinatal severe hypoxia in children should be extended open milk time.