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目的观察并研究通过化疗治疗颌面部非霍奇金淋巴瘤的疗效。方法 33例颌面部非霍奇金淋巴瘤首诊患者,给予以化疗为主的综合治疗,采用COP、CHOP方案为主的规范性治疗方案,观察治疗效果。结果 33例患者患病区及分期分析,颈部区20例,颌下区8例,舌根部1例,腭部1例,下唇1例,颊面部1例,腮腺1例;Ⅰ期3例,Ⅱ期13例,Ⅲ期12例,Ⅳ期5例。治疗后死亡8例。颈部区非霍奇金淋巴瘤的患病人数最多;舌根部的死亡率(100.0%)最高;Ⅳ期非霍奇金淋巴瘤的死亡比例(62.5%)最高。结论颈部区非霍奇金淋巴瘤的患病人数最多;舌根部的死亡率最高;Ⅳ期非霍奇金淋巴瘤的死亡比例最高。
Objective To observe and study the efficacy of chemotherapy for maxillofacial non-Hodgkin’s lymphoma. Methods Totally 33 patients with maxillofacial non-Hodgkin’s lymphoma were given chemotherapy-based comprehensive treatment. The COP and CHOP-based regimens were used to observe the therapeutic effect. Results The prevalence and staging of 33 patients were analyzed. There were 20 cases of cervical region, 8 cases of submandibular region, 1 tongue base, 1 palate, 1 lower lip, 1 buccal surface and 1 parotid gland. Stage Ⅰ 3 Cases, 13 cases of stage Ⅱ, 12 cases of stage Ⅲ, 5 cases of stage Ⅳ. 8 cases died after treatment. The incidence of non-Hodgkin’s lymphoma was the highest in the cervical region, the highest in the tongue base (100.0%), and the highest in the non-Hodgkin’s lymphoma (Ⅳ) (62.5%). Conclusions The incidence of non-Hodgkin’s lymphoma in the cervical region is the highest, the mortality in the tongue base is the highest, and the non-Hodgkin’s lymphoma in stage Ⅳ is the highest.