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目的探讨肺癌并发恶性胸腔积液的临床药物治疗体会。方法选取我院在2010年1月至2013年12月收治的肺癌并发恶性胸腔积液患者50例,随机分为两组,观察组应用顺铂联合沙培林治疗,对照组单用顺铂治疗,比较两组治疗效果。结果观察组治疗总有效率明显大于对照组(84.0%VS64.0%),治疗后生活质量改善情况明显优于对照组(88.0%VS56.0%),且P<0.05;两组不良反应比较无明显差异P>0.05。结论顺铂联合沙培林治疗肺癌并发恶性胸腔积液患者疗效较好,并对改善患者生活质量具有一定作用。
Objective To investigate the clinical drug treatment of lung cancer complicated with malignant pleural effusion. Methods Fifty patients with malignant pleural effusion of lung cancer admitted to our hospital from January 2010 to December 2013 were randomly divided into two groups. The observation group was treated with cisplatin combined with saponin, and the control group with cisplatin alone , Comparing the treatment effect of two groups. Results The total effective rate of the observation group was significantly higher than that of the control group (84.0% VS64.0%). The improvement of quality of life after treatment was significantly better than that of the control group (88.0% VS 56.0%), P <0.05; No significant difference P> 0.05. Conclusion Cisplatin combined with saponin in patients with lung cancer complicated with malignant pleural effusion has a better curative effect and has some effects on improving patients’ quality of life.